Zpět
doc. RNDr. Lucie Zemanová, Ph.D.
- Pracoviště: PřF - Katedra chemie
- docent
- E-mail: lucie.zemanova@uhk.cz
- Telefon: 493332776
- Budova: S
- Místnost: 73810 3. podlaží
Publikace na UHK
MONNIER, Charline, R. ANDRÝS, I. CASTELLINO, V. MIČKOVÁ, A. HALEČKOVÁ, J. LOSKOT, O. BENEK, L. ZEMANOVÁ. Immobilized animal liver microsomes: A versatile tool for efficient ester hydrolysis in chemo-enzymatic synthesis☆. METHODS. 2025, 240 (August), 35-46. ISSN 1046-2023.
PANEK, Dawid, A. PASIEKA, J. JONCZYK, M. GAWLINSKA, P. ZAREBA, A. SIWEK, M. WOLAK, B. MORDYL, M. GLUCH-LUTWIN, G. LATACZ, X. BRAZZOLOTTO, F. CHANTEGREIL, F. NACHON, J. ZDAROVA KARASOVA, J. PEJCHAL, M. MZIK, V. SESTAK, L. PRCHAL, J. ODVARKOVA, O. SOUKUP, J. KORABECNY, A. SORF, M. HAMŠÍKOVÁ, L. ZEMANOVÁ, L. MUCKOVA, N. VANOVA, P. DRYJA, K. SALAT, G. HÖFNER, K. WANNER, A. WIECKOWSKA, B. MALAWSKA. Multifunctional, Fluorene-Based Modulator of Cholinergic and GABAergic Neurotransmission as a Novel Drug Candidate for Palliative Treatment of Alzheimer's Disease. Angewandte Chemie International Edition. 2025, 64 (6), "Article number: e202420510". ISSN 1433-7851.
HALEČKOVÁ, Annamária, K. JURKOVÁ, J. HURDÁLEK, K. CHALUPOVÁ, V. SYROVÁ, D. KOZLOV, J. SVOBODOVÁ, R. ANDRÝS, O. KOZLOV, CH. MONNIER, R. ENDLICHER, A. SKARKA, K. MUSÍLEK, L. ZEMANOVÁ, O. BENEK. N-4-aminobenzyl-N'-(2-(2-phenylpyrrolidin)-2-oxoethyl)urea-based inhibitors of cyclophilin D-Preparation of distinct stereoisomers and comparative analysis of their in vitro bioactivity. Bioorganic Chemistry. 2025, 163 (August), "Article Number: 108743". ISSN 0045-2068.
HOUFKOVÁ, Aneta, M. SCHMIDT, O. BENEK, I. FABRIK, R. ANDRÝS, L. ZEMANOVÁ, O. SOUKUP, K. MUSÍLEK. New insights into the 17β-hydroxysteroid dehydrogenase type 10 and amyloid-β 42 derived cytotoxicity relevant to Alzheimer's disease. Alzheimers Research and Therapy. 2025, 17 (1), "Article Number: 170". ISSN 1758-9193.
ZOUHAROVA, Monika, P. HERMAN, L. BEDNAROVA, V. VETYSKOVA, R. HADRAVOVA, K. POSTULKOVA, L. ZEMANOVÁ, J. VONDRASEK, K. VYDRA BOUSOVA. Oligomerization Function of the Native Exon 5 Sequence of Ameloblastin Fused with Calmodulin. ACS Omega. 2025, 10 (8), 7741-7751. ISSN 2470-1343.
HANZLOVÁ, Michaela, B. SLAVIKOVÁ, M. MOROZOVOVÁ, K. MUSÍLEK, A. ROTTEROVÁ, L. ZEMANOVÁ, E. KUDOVÁ. C-3 Steroidal Hemiesters as Inhibitors of 17β-Hydroxysteroid Dehydrogenase Type 10. ACS Omega. 2024, 9 (10), 12116-12124. ISSN 2470-1343.
UNIVERZITA HRADEC KRÁLOVÉ. Deriváty 2-arylbenzothiazolu, způsob jejich přípravy a jejich použití, Původci: MUSÍLEK, Kamil, O. BENEK, L. ZEMANOVÁ2024. Číslo patentu: 310144.
HALEČKOVÁ, Annamária, V. SYROVÁ, A. JOKLOVÁ, T. VERNEROVÁ, J. HURDÁLEK, R. ENDLICHER, K. ŠALAMONOVÁ, P. BŮBELOVÁ, HFF. KURNIA, M. SCHMIDT, K. MUSÍLEK, L. ZEMANOVÁ, O. BENEK. Neuroprotective Effect of 2-(Benzyloxy)arylureas Is Not Related to CypD Inhibition nor Suppression of mPTP Opening. ACS Medicinal Chemistry Letters. 2024, 15 (10), 1756-1763. ISSN 1948-5875.
ANDRÝS, Rudolf, CH. MONNIER, E. ANTONIJEVIĆ MILJAKOVIĆ, V. MIČKOVÁ, K. MUSÍLEK, L. ZEMANOVÁ. Towards cost-effective drug discovery: Reusable immobilized enzymes for neurological disease research. Talanta. 2024, 276 (August), "Article Number: 126263". ISSN 0039-9140.
SCHMIDT, Monika, M. VAŠKOVÁ, A. ROTTEROVÁ, P. FIANDOVÁ, M. MIŠKEŘÍKOVÁ, L. ZEMANOVÁ, O. BENEK, K. MUSÍLEK. Physiologically relevant fluorescent assay for identification of 17β-hydroxysteroid dehydrogenase type 10 inhibitors. Journal of Neurochemistry. 2023, 167 (2), 154-167. ISSN 0022-3042.
HALEČKOVÁ, Annamária, O. BENEK, L. ZEMANOVÁ, R. DOLEŽAL, K. MUSÍLEK. Small-molecule inhibitors of cyclophilin D as potential therapeutics in mitochondria-related diseases. Medicinal Research Reviews. 2022, 42 (5), 1822-1855. ISSN 0198-6325.
SCHMIDT, Monika, O. BENEK, L. VINKLÁŘOVÁ, M. HRABINOVA, L. ZEMANOVÁ, M. CHRIBEK, V. KRALOVA, L. HROCH, R. DOLEŽAL, A. LYČKA, L. PRCHAL, D. JUN, L. AITKEN, F. GUNN-MOORE, K. KUČA, K. MUSÍLEK. Benzothiazolyl Ureas are Low Micromolar and Uncompetitive Inhibitors of 17 beta-HSD10 with Implications to Alzheimer's Disease Treatment. International journal of molecular sciences. 2020, 21 (6), "Article Number: 2059". ISSN 1661-6596.
ZEMANOVÁ, Lucie, M. VAŠKOVÁ, M. SCHMIDT, J. ROUBALOVÁ, A. HALEČKOVÁ, O. BENEK, K. MUSÍLEK. RNase T1 Refolding Assay for Determining Mitochondrial Cyclophilin D Activity: A Novel In Vitro Method Applicable in Drug Research and Discovery. Biochemistry. 2020, 59 (17), 1680-1687. ISSN 0006-2960.
ZEMANOVÁ, Lucie, H. NAVRÁTILOVÁ, R. ANDRÝS, K. ŠPERKOVÁ, J. ANDREJS, K. KOZÁKOVÁ, M. MEIER, G. MÖELLER, E. NOVOTNÁ, M. ŠAFR, J. ADAMSKI, V. WSÓL. Initial characterization of human DHRS1 (SDR19C1), a member of the short chain dehydrogenase/reductase superfamily. Journal of steroid biochemistry and molecular biology. 2019, 185 (January), 80-89. ISSN 0960-0760.
Životopis
Pozice a funkce na pracovišti
od 2019: docent
2018 - 2019: odborný asistent
Vzdělání, kvalifikace
2006 - 2009: doktorské studium - Patobiochemie a xenobiochemie, Farmaceutická fakulta v Hradci Králové, Univerzita Karlova
2004 - 2006: magisterské studium - Analýza biologických materiálů, Fakulta chemicko-technologická, Univerzita Pardubice
2001 - 2004: bakalářské studium - Klinická biologie a chemie, Fakulta chemicko-technologická, Univerzita Pardubice
