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Mgr. Eugenie Nepovimová, Ph.D.

Mgr. Eugenie Nepovimová, Ph.D.
Akademický senát UHK
členka komory akademických pracovníků za PřF
Pracoviště: PřF - Katedra chemie
odborný asistent
E-mail:
Telefon: 493332792
Budova: S
Místnost: 73860 3. podlaží

Publikace na UHK

JUROWSKI, Kamil, M. NOGA, D. KOBYLARZ, L. NIŽNÍK, A. MACHLANSKA, E. NEPOVIMOVÁ, K. KUČA. Cannabis-derived food products: a global review of THC exposure, safety and forensic frameworks. Food and chemical toxicology. 2026, 217 (November), "Article Number: 116285". ISSN 0278-6915.

LI, Junyao, X. HUANG, W. WEI, X. WANG, L. YOU, E. NEPOVIMOVÁ, Q. WU, K. KUČA. Circadian PER2 promotes T-2 toxin-induced immunosenescence by activating the hippo/MST1 signaling in macrophages. Toxicology. 2026, 525 (September), "Article number: 154501". ISSN 0300-483X.

YOU, Li, E. NEPOVIMOVÁ, Q. WU, K. KUČA. Circadian rhythm, oxidative stress, and cancer immunosuppression. Archives of toxicology. 2026, 100 (9), 3857-3881. ISSN 0340-5761.

ZHAO, Baimei, S. TAN, J. LI, E. NEPOVIMOVÁ, Q. WU, K. KUČA. Deoxynivalenol induces macrophage extracellular trap formation via the PER2–c-Myc–ROS Axis. Toxicology. 2026, 526 (November), "Article number: 154549". ISSN 0300-483X.

LI, Yihao, J. LI, B. ZHAO, Z. YUAN, T. NIE, E. NEPOVIMOVÁ, Q. WU, K. KUČA. Deoxynivalenol-induced circadian CLOCK oscillation disruption promotes RAW264.7 macrophage immunosenescence by unleashing cGAS-STING signaling. Ecotoxicology and Environmental Safety. 2026, 313 (March), "Article number: 119983". ISSN 0147-6513.

RYSANEK, David, Ž. CHRIENOVÁ, D. STARY, M. BAJDA, J. NOVAK, P. VASICOVA, J. KROUPOVA, R. ANDRÝS, A. SKARKA, E. ROUSAROVA, J. CAPEK, T. ROUSAR, Z. MILOVANOVIC, J. GRUJIC-MILANOVIC, VM. JACEVIC, JN. KOLLA, M. POPR, D. MAURENCOVA, P. OLEKŠÁK, L. FRESSER, K. KUČA, Z. HODNY, E. NEPOVIMOVÁ. In silico screening, synthesis, and biological evaluation of pyrazolopyrimidine-derived mTOR inhibitors for anticancer and senomorphic effects. Cancer Cell International. 2026, 26 (1), "Article number: 247". ISSN 1475-2867.

JOMOVÁ, Klaudia, S. ALOMAR, R. VALKO, L. FRESSER, E. NEPOVIMOVÁ, K. KUČA, M. VALKO. Interplay of oxidative stress and antioxidant mechanisms in cancer development and progression. Archives of toxicology. 2026, 100 (1), 27-73. ISSN 0340-5761.

LI, Junyao, E. NEPOVIMOVÁ, A. GRUNDEL, L. PETER, Q. WU, K. KUČA. Macrophage Extracellular Traps in Immunity and Cancer. Advanced Science. 2026, 13 (35), "Article number: e20421". ISSN 2198-3844.

JUROWSKI, Kamil, L. NIZNIK, M. NOGA, D. KOBYLARZ, A. FRYDRYCH, O. FIJALKOWSKA, E. NEPOVIMOVÁ, K. KUČA. Navigating through toxicological data: review of toxicological databases and sources in the interdisciplinary context including-chemicals, cosmetics, pharmaceuticals and forensics. Archives of toxicology. 2026, 100 (7), 2779–2812. ISSN 0340-5761.

JOMOVA, Klaudia, SY. ALOMAR, R. VALKO, E. NEPOVIMOVÁ, K. KUČA, M. VALKO. Oxidative stress and inflammation in neurodegenerative disorders. Archives of toxicology. 2026, 100 (10), 4367-4445. ISSN 0340-5761.

NIDHI, Nidhi, I. BARDWAJ, K. DULTA, E. NEPOVIMOVÁ, K. KUČA, M. CHOUDHARY, P. MANDYAL, A. CHOUDHARY, L. PETER. Role of Underutilized Plant-Derived Metal Oxide-Based Nanoparticles Against Prostate Cancer. In: Underutilized Plants Based-Nanoparticles: Herbal Remedy to Treat Human Diseases: Underutilized Plants and Nanoparticles, Cham: Springer Nature, 2026. ISBN 978-3-032-20384-7.

KUMAR, Harsh, S. GULERIA, P. JHA, DS. DHANJAL, E. NEPOVIMOVÁ, SS. SANA, AM. SHAIKH, B. KOVÁCS, E. HARSÁNYI. Sustainable utilization of fruit waste in cereal-based breakfast foods: Pre-clinical and clinical perspectives on safety and nutritional benefits. Current Research in Food Science. 2026, 12 (January), "Article number: 101284". ISSN 2665-9271.

NIE, Tong, J. LI, S. TAN, S. CHEN, D. YANG, E. NEPOVIMOVÁ, Q. WU, K. KUČA. T-2 toxin disrupts Alzheimer’s-relevant App/Tau homeostasis via circadian-p53-senescence crosstalk: Evidence from human neuroblastoma cells. NeuroToxicology. 2026, 117 (December), "Article number: 103559". ISSN 0161-813X.

TAN, Shiqing, E. NEPOVIMOVÁ, M. VALKO, K. JOMOVA, Q. WU, K. KUČA. The cGAS-STING pathway in senescence and aging-related diseases: mechanisms and therapeutic opportunities. Cell Communication and Signaling. 2026, 24 (1), "Article Number: 292". ISSN 1478-811X.

TAN, S., X. HUANG, J. LI, E. NEPOVIMOVÁ, M. VALKO, Q. WU, K. KUČA. The Hippo-YAP/TAZ axis: A central signaling hub integrating diverse cues to regulate cellular senescence. Mechanisms of Ageing and Development. 2026, 232 (August), "Article Number: 112208". ISSN 0047-6374.

OLEKŠÁK, Patrik, D. RYSANEK, M. VANCUROVA, J. NOVAK, D. MAURENCOVA, E. ROUSAROVA, J. CAPEK, T. ROUSAR, K. VALES, V. ŠKOPEK, MJ. MASLOWSKA, K. GUMAUSKAITE, G. STANKUS, K. KUČA, R. ANDRÝS, A. SKARKA, M. LÍSA, L. FRESSER, S. SUROVCOVÁ, Ž. CHRIENOVÁ, M. POPR, E. NEPOVIMOVÁ, Z. HODNY. The structure-activity relationship study of torkinib derivatives as mTOR inhibitors with senolytic and STAT3 inhibitory activities. Bioorganic Chemistry. 2026, 176 (July), "Article number: 109868". ISSN 0045-2068.

UNIVERZITA HRADEC KRÁLOVÉ. 1-(3-Chlor-4-hydroxyfenyl)-3-(6-((trifluormethyl)thio)benzo[d]thiazol-2-yl)močovina pro použití pro léčbu rakoviny, Původci: NEPOVIMOVÁ, Eugenie, D. RYŠÁNEK, Ž. CHRIENOVÁ, P. OLEKŠÁK, K. KUČA2025. Číslo patentu: 310 416.

PATOCKA, Jiri, S. SHARMA, Z. NAVRATILOVA, N. SINGH, R. JELINKOVA, N. MEHBOOB, P. OLEKŠÁK, E. NEPOVIMOVÁ, K. KUČA. Anticholinesterases Traits Inbuilt in Buxaceae Plant Extracts against Alzheimer's Disease. Current Neuropharmacology. 2025, 23 (10), 1137-1155. ISSN 1570-159X.

KUMAR, Harsh, S. GULERIA, N. KIMTA, E. NEPOVIMOVÁ, SD. DHANJAL, N. SETHI, T. SUTHAR, AM. SHAIKH, KB. BELA, E. HARSANYI. Applications of citrus peels valorisation in circular bioeconomy. Journal of Agriculture and Food Research. 2025, 20 (April), "Article number: 101780". ISSN 2666-1543.

AMIR, A., S. HUSSAIN, S. SHAH, R. HABIB, Z. MUNEER, E. NEPOVIMOVÁ, K. KUČA, S. NURULAIN. Association of BCHE gene SNP rs1803274 (K-variant) and rs3495 with obesity in Pakistani population group. International Journal of Obesity. 2025, 49 (5), 881-887. ISSN 0307-0565.